Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor

The monoclonal antibody hGR-2 F6 has been raised against the human glucagon receptor and shown to act as a competitive antagonist. As a first step in the structural characterization of the receptor, the crystal structure of the Fab fragment from this antibody is reported at 2.1 resolution. The hGR-2...

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Những tác giả chính: Wright, L, Brzozowski, A, Hubbard, R, Pike, A, Roberts, S, Skovgaard, R, Svendsen, I, Vissing, H, Bywater, R
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2000