Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor
The monoclonal antibody hGR-2 F6 has been raised against the human glucagon receptor and shown to act as a competitive antagonist. As a first step in the structural characterization of the receptor, the crystal structure of the Fab fragment from this antibody is reported at 2.1 resolution. The hGR-2...
Main Authors: | Wright, L, Brzozowski, A, Hubbard, R, Pike, A, Roberts, S, Skovgaard, R, Svendsen, I, Vissing, H, Bywater, R |
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Format: | Journal article |
Language: | English |
Published: |
2000
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