Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand.

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand.

OBJECTIVE: GDF5 and FRZB have been proposed as genetic loci conferring susceptibility to osteoarthritis (OA); however, the results of several studies investigating the association of OA with the rs143383 polymorphism of the GDF5 gene or the rs7775 and rs288326 polymorphisms of the FRZB gene have bee...

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Detalhes bibliográficos
Principais autores: Evangelou, E, Chapman, K, Meulenbelt, I, Karassa, F, Loughlin, J, Carr, A, Doherty, M, Doherty, S, Gómez-Reino, J, Gonzalez, A, Halldorsson, B, Hauksson, V, Hofman, A, Hart, D, Ikegawa, S, Ingvarsson, T, Jiang, Q, Jonsdottir, I, Jonsson, H, Kerkhof, H, Kloppenburg, M, Lane, N, Li, J, Lories, R, van Meurs, J
Formato: Journal article
Idioma:English
Publicado em: 2009

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