Allosteric beta-propeller signalling in TolB and its manipulation by translocating colicins.
The Tol system is a five-protein assembly parasitized by colicins and bacteriophages that helps stabilize the Gram-negative outer membrane (OM). We show that allosteric signalling through the six-bladed beta-propeller protein TolB is central to Tol function in Escherichia coli and that this is subve...
Main Authors: | Bonsor, D, Hecht, O, Vankemmelbeke, M, Sharma, A, Krachler, A, Housden, N, Lilly, K, James, R, Moore, G, Kleanthous, K |
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Format: | Journal article |
Language: | English |
Published: |
2009
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