An alternative conformation of the T-cell receptor alpha constant region.
Alphabeta T-cell receptors (TcRs) play a central role in cellular immune response. They are members of the Ig superfamily, with extracellular regions of the alpha and beta chains each comprising a V-type domain and a C-type domain. We have determined the ectodomain structure of an alphabeta TcR, whi...
Main Authors: | van Boxel, G, Holmes, S, Fugger, L, Jones, E |
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Format: | Journal article |
Language: | English |
Published: |
2010
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