An alternative conformation of the T-cell receptor alpha constant region.
Alphabeta T-cell receptors (TcRs) play a central role in cellular immune response. They are members of the Ig superfamily, with extracellular regions of the alpha and beta chains each comprising a V-type domain and a C-type domain. We have determined the ectodomain structure of an alphabeta TcR, whi...
Autors principals: | van Boxel, G, Holmes, S, Fugger, L, Jones, E |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
2010
|
Ítems similars
-
Some lessons from the systematic production and structural analysis of soluble (alpha)(beta) T-cell receptors.
per: van Boxel, G, et al.
Publicat: (2009) -
ANALYSIS OF THE CONSTANT AND VARIABLE REGIONS OF THE ALPHA-SUBUNIT OF THE T-CELL ANTIGEN RECEPTOR
per: Acuto, O, et al.
Publicat: (1985) -
Sampling alternative conformational states of transporters and receptors with AlphaFold2
per: Diego del Alamo, et al.
Publicat: (2022-03-01) -
Production and characterization of antibody probes directed at constant regions of the alpha and beta subunit of the human T cell receptor.
per: Fabbi, M, et al.
Publicat: (1985) -
The conformation of the main immunogenic region on the alpha-subunit of muscle acetylcholine receptor is affected by neighboring receptor subunits.
per: Fostieri, E, et al.
Publicat: (2000)