An alternative conformation of the T-cell receptor alpha constant region.

An alternative conformation of the T-cell receptor alpha constant region.

Alphabeta T-cell receptors (TcRs) play a central role in cellular immune response. They are members of the Ig superfamily, with extracellular regions of the alpha and beta chains each comprising a V-type domain and a C-type domain. We have determined the ectodomain structure of an alphabeta TcR, whi...

Полное описание

Библиографические подробности
Главные авторы:	van Boxel, G, Holmes, S, Fugger, L, Jones, E
Формат:	Journal article
Язык:	English
Опубликовано:	2010

Схожие документы

Some lessons from the systematic production and structural analysis of soluble (alpha)(beta) T-cell receptors.
по: van Boxel, G, и др.
Опубликовано: (2009)

ANALYSIS OF THE CONSTANT AND VARIABLE REGIONS OF THE ALPHA-SUBUNIT OF THE T-CELL ANTIGEN RECEPTOR
по: Acuto, O, и др.
Опубликовано: (1985)

Sampling alternative conformational states of transporters and receptors with AlphaFold2
по: Diego del Alamo, и др.
Опубликовано: (2022-03-01)

Production and characterization of antibody probes directed at constant regions of the alpha and beta subunit of the human T cell receptor.
по: Fabbi, M, и др.
Опубликовано: (1985)

The conformation of the main immunogenic region on the alpha-subunit of muscle acetylcholine receptor is affected by neighboring receptor subunits.
по: Fostieri, E, и др.
Опубликовано: (2000)

Modeling the interactions of a peptide-major histocompatibility class I ligand with its receptors. I. Recognition by two alpha beta T cell receptors.
по: Rognan, D, и др.
Опубликовано: (2000)

Harmonic conformal flows on manifolds of constant curvature
по: Fawaz Amine
Опубликовано: (2007-09-01)

Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits.
по: Jones, A, и др.
Опубликовано: (2009)

Induced fit versus conformational selection: From rate constants to fluxes… and back to rate constants
по: Georges Vauquelin, и др.
Опубликовано: (2021-10-01)

Determination of the Strong Coupling Constant by the ALPHA Collaboration
по: Korzec Tomasz
Опубликовано: (2018-01-01)

Conformal perturbation theory for n-point functions: structure constant deformation
по: Benjamin A. Burrington, и др.
Опубликовано: (2024-06-01)

Generalized cosmological constant from gauging Maxwell-conformal algebra
по: Salih Kibaroğlu, и др.
Опубликовано: (2020-04-01)

Yamabe constant evolution and monotonicity along the conformal Ricci flow
по: Yanlin Li, и др.
Опубликовано: (2022-04-01)

Alternate conformational trajectories in ribosome translocation.
по: Jose L Alejo, и др.
Опубликовано: (2024-08-01)

Dopamine-induced conformational changes in alpha-synuclein.
по: Tiago F Outeiro, и др.
Опубликовано: (2009-09-01)

T cell receptor alpha chain polymorphisms in multiple sclerosis.
по: Hashimoto, L, и др.
Опубликовано: (1992)

The staphylococcal alpha-toxin pore has a flexible conformation.
по: Vécsey-Semjén, B, и др.
Опубликовано: (1999)

$(\alpha,\beta)$-Metrics with killing $\beta$ of constant length
по: Tayebeh Tabatabaeifar, и др.
Опубликовано: (2020-02-01)

Dynamic methylation and expression of alternative promoters for oestrogen receptor alpha in cell line models of fulvestrant resistance
по: Juliane Albrecht, и др.
Опубликовано: (2025-01-01)

An alternative formula for the constant growth model
по: Juan A. Forsyth
Опубликовано: (2019-11-01)

Alternative conformations of a major antigenic site on RSV F.
по: Harrison G Jones, и др.
Опубликовано: (2019-07-01)

Conformal structure of singularities in some varying fundamental constants bimetric cosmologies
по: Konrad Marosek, и др.
Опубликовано: (2024-09-01)

Functional isotypes are not encoded by the constant region genes of the beta subunit of the T cell receptor for antigen/major histocompatibility complex.
по: Royer, H, и др.
Опубликовано: (1984)

Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type
по: Elisabet Ihse, и др.
Опубликовано: (2017-08-01)

Structure prediction of alternative protein conformations
по: Patrick Bryant, и др.
Опубликовано: (2024-08-01)

Workplace alternatives – confront, conform, capitulate
по: A Grobler
Опубликовано: (2014-01-01)

MEASUREMENT OF THE STRONG COUPLING-CONSTANT ALPHA-S FOR BOTTOM QUARKS AT THE Z(0) RESONANCE
по: Adeva, B, и др.
Опубликовано: (1991)

Autocrine regulation of cell proliferation by estrogen receptor-alpha in estrogen receptor-alpha-positive breast cancer cell lines
по: Pan Zhongzong, и др.
Опубликовано: (2009-01-01)

The role of non-coding regions of the alpha-synuclein gene in protein expression and the determination of alternatively spliced alpha-synuclein isoforms in oxidatively stressed cells
по: Williams, SE
Опубликовано: (2013)

Kinetic rate constant prediction supports the conformational selection mechanism of protein binding.
по: Iain H Moal, и др.
Опубликовано: (2012-01-01)

Inflationary non-Gaussianities in alpha vacua and consistency with conformal symmetries
по: Arhum Ansari, и др.
Опубликовано: (2024-10-01)

Conformational equilibria in monomeric alpha-synuclein at the single-molecule level.
по: Massimo Sandal, и др.
Опубликовано: (2008-01-01)

AlphaFold predictions of fold-switched conformations are driven by structure memorization
по: Devlina Chakravarty, и др.
Опубликовано: (2024-08-01)

Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha
по: Mingyi Chen, и др.
Опубликовано: (2005-12-01)

The signalling conformation of the insulin receptor ectodomain
по: Felix Weis, и др.
Опубликовано: (2018-10-01)

Conformational Dynamics of Nonenveloped Circovirus Capsid to the Host Cell Receptor
по: Jiarong Li, и др.
Опубликовано: (2020-10-01)

Elevated concentrations cause upright alpha-synuclein conformation at lipid interfaces
по: Steven J. Roeters, и др.
Опубликовано: (2023-09-01)

In Silico Exploration of Alternative Conformational States of VDAC
по: Carmen Mannella
Опубликовано: (2023-04-01)

Empowering AlphaFold2 for protein conformation selective drug discovery with AlphaFold2-RAVE
по: Xinyu Gu, и др.
Опубликовано: (2024-09-01)

Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational change and cause signalling bias
по: Gorvin, C, и др.
Опубликовано: (2018)