An alternative conformation of the T-cell receptor alpha constant region.

Alphabeta T-cell receptors (TcRs) play a central role in cellular immune response. They are members of the Ig superfamily, with extracellular regions of the alpha and beta chains each comprising a V-type domain and a C-type domain. We have determined the ectodomain structure of an alphabeta TcR, whi...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: van Boxel, G, Holmes, S, Fugger, L, Jones, E
Format: Journal article
Sprache:English
Veröffentlicht: 2010