Association mapping in structured populations.
The use, in association studies, of the forthcoming dense genomewide collection of single-nucleotide polymorphisms (SNPs) has been heralded as a potential breakthrough in the study of the genetic basis of common complex disorders. A serious problem with association mapping is that population structu...
Main Authors: | Pritchard, J, Stephens, M, Rosenberg, N, Donnelly, P |
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Format: | Journal article |
Language: | English |
Published: |
2000
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