Electrophilic fluorination of organosilanes.
The fluorination of organosilanes with the silyl groups directly attached or adjacent to an aryl or alkenyl group has been only very recently examined despite the fact that the corresponding fluorinated products are synthetically useful building blocks. In these reactions, the silyl group enhances t...
| Үндсэн зохиолчид: | , |
|---|---|
| Формат: | Journal article |
| Хэл сонгох: | English |
| Хэвлэсэн: |
2006
|
| _version_ | 1826261317985501184 |
|---|---|
| author | Tredwell, M Gouverneur, V |
| author_facet | Tredwell, M Gouverneur, V |
| author_sort | Tredwell, M |
| collection | OXFORD |
| description | The fluorination of organosilanes with the silyl groups directly attached or adjacent to an aryl or alkenyl group has been only very recently examined despite the fact that the corresponding fluorinated products are synthetically useful building blocks. In these reactions, the silyl group enhances the reactivity of the pi-nucleophile and controls the sense of regiochemistry upon addition of the electrophilic source of fluorine. These reactions take advantage of the beta effect of the silicon-carbon bond and recent results from the literature revealed that this chemistry allows for the preparation of a variety of novel fluorinated building blocks including enantio-enriched derivatives. |
| first_indexed | 2024-03-06T19:19:30Z |
| format | Journal article |
| id | oxford-uuid:199677dd-73cf-4820-b5ea-2752eb78acb2 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:19:30Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:199677dd-73cf-4820-b5ea-2752eb78acb22022-03-26T10:49:41ZElectrophilic fluorination of organosilanes.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:199677dd-73cf-4820-b5ea-2752eb78acb2EnglishSymplectic Elements at Oxford2006Tredwell, MGouverneur, VThe fluorination of organosilanes with the silyl groups directly attached or adjacent to an aryl or alkenyl group has been only very recently examined despite the fact that the corresponding fluorinated products are synthetically useful building blocks. In these reactions, the silyl group enhances the reactivity of the pi-nucleophile and controls the sense of regiochemistry upon addition of the electrophilic source of fluorine. These reactions take advantage of the beta effect of the silicon-carbon bond and recent results from the literature revealed that this chemistry allows for the preparation of a variety of novel fluorinated building blocks including enantio-enriched derivatives. |
| spellingShingle | Tredwell, M Gouverneur, V Electrophilic fluorination of organosilanes. |
| title | Electrophilic fluorination of organosilanes. |
| title_full | Electrophilic fluorination of organosilanes. |
| title_fullStr | Electrophilic fluorination of organosilanes. |
| title_full_unstemmed | Electrophilic fluorination of organosilanes. |
| title_short | Electrophilic fluorination of organosilanes. |
| title_sort | electrophilic fluorination of organosilanes |
| work_keys_str_mv | AT tredwellm electrophilicfluorinationoforganosilanes AT gouverneurv electrophilicfluorinationoforganosilanes |