The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid.

Arylamine N-acetyltransferases which acetylate and inactivate isoniazid, an anti-tubercular drug, are found in mycobacteria including Mycobacterium smegmatis and Mycobacterium tuberculosis. We have solved the structure of arylamine N-acetyltransferase from M. smegmatis at a resolution of 1.7 A as a...

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Príomhchruthaitheoirí: Sandy, J, Mushtaq, A, Kawamura, A, Sinclair, J, Sim, E, Noble, M
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2002