Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk.

Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk.

Several lines of evidence implicate mitochondrial dysfunction in the development of cancer. To test the hypothesis that common mtDNA variation influences the risk of colorectal cancer (CRC), we genotyped 132 tagging mtDNA variants in a sample of 2854 CRC cases and 2822 controls. The variants examine...

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Dettagli Bibliografici
Autori principali:	Webb, E, Broderick, P, Chandler, I, Lubbe, S, Penegar, S, Tomlinson, I, Houlston, R
Natura:	Journal article
Lingua:	English
Pubblicazione:	2008

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