Mapping epigenetic changes to the host cell genome induced by Burkholderia pseudomallei reveals pathogen-specific and pathogen-generic signatures of infection

The potential for epigenetic changes in host cells following microbial infection has been widely suggested, but few examples have been reported. We assessed genome-wide patterns of DNA methylation in human macrophage-like U937 cells following infection with Burkholderia pseudomallei, an intracellula...

Full description

Bibliographic Details
Main Authors: Cizmeci, D, Dempster, E, Champion, O, Wagley, S, Akman, O, Prior, J, Soyer, O, Mill, J, Titball, R
Format: Journal article
Language:English
Published: Springer Nature 2016