On the histone lysine methyltransferase activity of fungal metabolite chaetocin.

On the histone lysine methyltransferase activity of fungal metabolite chaetocin.

Histone lysine methyltransferases (HKMTs) are an important class of targets for epigenetic therapy. 1 (chaetocin), an epidithiodiketopiperazine (ETP) natural product, has been reported to be a specific inhibitor of the SU(VAR)3-9 class of HKMTs. We have studied the inhibition of the HKMT G9a by 1 an...

书目详细资料
Main Authors:	Cherblanc, F, Chapman, K, Reid, J, Borg, A, Sundriyal, S, Alcazar-Fuoli, L, Bignell, E, Demetriades, M, Schofield, C, DiMaggio, P, Brown, R, Fuchter, M
格式:	Journal article
语言:	English
出版:	2013

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