Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia

Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia

MicroRNAs are well characterized in their role in silencing gene expression by targeting 3´-UTR of mRNAs in cytoplasm. However, recent studies have shown that miRNAs have a role in the regulation of genes in the nucleus, where they are abundantly located. We show here that in mouse endothelial cell...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Laitinen, P, Väänänen, M-A, Kolari, I-L, Mäkinen, PI, Kaikkonen, MU, Weinberg, MS, Morris, KV, Korhonen, P, Malm, T, Ylä-Herttuala, S, Roberts, TC, Turunen, MP, Turunen, TA
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2022

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