Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.

Following peripheral nerve injury microglia accumulate within the spinal cord and adopt a proinflammatory phenotype a process which contributes to the development of neuropathic pain. We have recently shown that neuregulin-1, a growth factor released following nerve injury, activates erbB 2, 3, and...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Calvo, M, Zhu, N, Grist, J, Ma, Z, Loeb, J, Bennett, D
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2011