Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.

Following peripheral nerve injury microglia accumulate within the spinal cord and adopt a proinflammatory phenotype a process which contributes to the development of neuropathic pain. We have recently shown that neuregulin-1, a growth factor released following nerve injury, activates erbB 2, 3, and...

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Váldodahkkit: Calvo, M, Zhu, N, Grist, J, Ma, Z, Loeb, J, Bennett, D
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2011