Exchangeability of mammalian DNA ligases between base excision repair pathways.

In mammalian cells, DNA ligase IIIalpha and DNA ligase I participate in the short- and long-patch base excision repair pathways, respectively. Using an in vitro repair assay employing DNA ligase-depleted cell extracts and DNA substrates containing a single lesion repaired either through short-patch...

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Hlavní autoři: Sleeth, K, Robson, R, Dianov, G
Médium: Journal article
Jazyk:English
Vydáno: 2004