Exchangeability of mammalian DNA ligases between base excision repair pathways.
In mammalian cells, DNA ligase IIIalpha and DNA ligase I participate in the short- and long-patch base excision repair pathways, respectively. Using an in vitro repair assay employing DNA ligase-depleted cell extracts and DNA substrates containing a single lesion repaired either through short-patch...
Principais autores: | , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2004
|