A mechanism of sialylation functionally silences the hyaluronan receptor LYVE-1 in lymphatic endothelium.

The major lymphatic endothelial hyaluronan receptor LYVE-1, a Link superfamily glycoprotein similar to the hyaluronan-binding/inflammatory leukocyte homing receptor CD44, was initially implicated in hyaluronan (HA)-mediated cell adhesion and lymph-borne hyaluronan metabolism. However, the apparently...

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Autori principali: Nightingale, T, Frayne, M, Clasper, S, Banerji, S, Jackson, D
Natura: Journal article
Lingua:English
Pubblicazione: 2009