The bonobo genome compared with the chimpanzee and human genomes

Two African apes are the closest living relatives of humans: the chimpanzee (Pan troglodytes) and the bonobo (Pan paniscus). Although they are similar in many respects, bonobos and chimpanzees differ strikingly in key social and sexual behaviours, and for some of these traits they show more similari...

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Main Authors: Prüfer, K, Munch, K, Hellmann, I, Akagi, K, Miller, JR, Walenz, B, Koren, S, Sutton, G, Kodira, C, Winer, R, Knight, JR, Mullikin, J, Meader, S, Ponting, C, Lunter, G, Higashino, S, Hobolth, A, Dutheil, J, Karakoç, E, Alkan, C, Sajjadian, S, Catacchio, C, Ventura, M, Marques-Bonet, T, Eichler, E
Format: Journal article
Language:English
Published: 2012
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author Prüfer, K
Munch, K
Hellmann, I
Akagi, K
Miller, JR
Walenz, B
Koren, S
Sutton, G
Kodira, C
Winer, R
Knight, JR
Mullikin, J
Meader, S
Ponting, C
Lunter, G
Higashino, S
Hobolth, A
Dutheil, J
Karakoç, E
Alkan, C
Sajjadian, S
Catacchio, C
Ventura, M
Marques-Bonet, T
Eichler, E
author_facet Prüfer, K
Munch, K
Hellmann, I
Akagi, K
Miller, JR
Walenz, B
Koren, S
Sutton, G
Kodira, C
Winer, R
Knight, JR
Mullikin, J
Meader, S
Ponting, C
Lunter, G
Higashino, S
Hobolth, A
Dutheil, J
Karakoç, E
Alkan, C
Sajjadian, S
Catacchio, C
Ventura, M
Marques-Bonet, T
Eichler, E
author_sort Prüfer, K
collection OXFORD
description Two African apes are the closest living relatives of humans: the chimpanzee (Pan troglodytes) and the bonobo (Pan paniscus). Although they are similar in many respects, bonobos and chimpanzees differ strikingly in key social and sexual behaviours, and for some of these traits they show more similarity with humans than with each other. Here we report the sequencing and assembly of the bonobo genome to study its evolutionary relationship with the chimpanzee and human genomes. We find that more than three per cent of the human genome is more closely related to either the bonobo or the chimpanzee genome than these are to each other. These regions allow various aspects of the ancestry of the two ape species to be reconstructed. In addition, many of the regions that overlap genes may eventually help us understand the genetic basis of phenotypes that humans share with one of the two apes to the exclusion of the other. © 2012 Macmillan Publishers Limited. All rights reserved.
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spelling oxford-uuid:1a10a9f0-c9d9-4dad-92dc-7990836af1ef2022-03-26T10:52:39ZThe bonobo genome compared with the chimpanzee and human genomesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1a10a9f0-c9d9-4dad-92dc-7990836af1efEnglishSymplectic Elements at Oxford2012Prüfer, KMunch, KHellmann, IAkagi, KMiller, JRWalenz, BKoren, SSutton, GKodira, CWiner, RKnight, JRMullikin, JMeader, SPonting, CLunter, GHigashino, SHobolth, ADutheil, JKarakoç, EAlkan, CSajjadian, SCatacchio, CVentura, MMarques-Bonet, TEichler, ETwo African apes are the closest living relatives of humans: the chimpanzee (Pan troglodytes) and the bonobo (Pan paniscus). Although they are similar in many respects, bonobos and chimpanzees differ strikingly in key social and sexual behaviours, and for some of these traits they show more similarity with humans than with each other. Here we report the sequencing and assembly of the bonobo genome to study its evolutionary relationship with the chimpanzee and human genomes. We find that more than three per cent of the human genome is more closely related to either the bonobo or the chimpanzee genome than these are to each other. These regions allow various aspects of the ancestry of the two ape species to be reconstructed. In addition, many of the regions that overlap genes may eventually help us understand the genetic basis of phenotypes that humans share with one of the two apes to the exclusion of the other. © 2012 Macmillan Publishers Limited. All rights reserved.
spellingShingle Prüfer, K
Munch, K
Hellmann, I
Akagi, K
Miller, JR
Walenz, B
Koren, S
Sutton, G
Kodira, C
Winer, R
Knight, JR
Mullikin, J
Meader, S
Ponting, C
Lunter, G
Higashino, S
Hobolth, A
Dutheil, J
Karakoç, E
Alkan, C
Sajjadian, S
Catacchio, C
Ventura, M
Marques-Bonet, T
Eichler, E
The bonobo genome compared with the chimpanzee and human genomes
title The bonobo genome compared with the chimpanzee and human genomes
title_full The bonobo genome compared with the chimpanzee and human genomes
title_fullStr The bonobo genome compared with the chimpanzee and human genomes
title_full_unstemmed The bonobo genome compared with the chimpanzee and human genomes
title_short The bonobo genome compared with the chimpanzee and human genomes
title_sort bonobo genome compared with the chimpanzee and human genomes
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