Smoking and reconstruction of the anterior cruciate ligament.

We sought to determine whether smoking affected the outcome of reconstruction of the anterior cruciate ligament. We analysed the results of 66 smokers (group 1 with a mean follow-up of 5.67 years (1.1 to 12.7)) and 238 non-smokers (group 2 with a mean follow-up of 6.61 years (1.2 to 11.5)), who were...

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Main Authors: Karim, A, Pandit, H, Murray, J, Wandless, F, Thomas, N
Format: Journal article
Language:English
Published: 2006
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author Karim, A
Pandit, H
Murray, J
Wandless, F
Thomas, N
author_facet Karim, A
Pandit, H
Murray, J
Wandless, F
Thomas, N
author_sort Karim, A
collection OXFORD
description We sought to determine whether smoking affected the outcome of reconstruction of the anterior cruciate ligament. We analysed the results of 66 smokers (group 1 with a mean follow-up of 5.67 years (1.1 to 12.7)) and 238 non-smokers (group 2 with a mean follow-up of 6.61 years (1.2 to 11.5)), who were statistically similar in age, gender, graft type, fixation and associated meniscal and chondral pathology. The assessment was performed using the International Knee Documentation Committee form and serial cruciometer readings. Poor outcomes were reported in group 1 for the mean subjective International Knee Documentation Committee score (p < 0.001), the frequency (p = 0.005) and intensity (p = 0.005) of pain, a side-to-side difference in knee laxity (p = 0.001) and the use of a four-strand hamstring graft (p = 0.015). Patients in group 1 were also less likely to return to their original level of pre-injury sport (p = 0.003) and had an overall worse final 7 International Knee Documentation Committee grade score (p = 0.007). Despite the well-known negative effects of smoking on tissue healing, the association with an inferior outcome after reconstruction of the anterior cruciate ligament has not previously been described and should be included in the pre-operative counselling of patients undergoing the procedure.
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spelling oxford-uuid:1a2c34b4-7566-435a-82d1-cc1923ff24ac2022-03-26T10:53:19ZSmoking and reconstruction of the anterior cruciate ligament.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1a2c34b4-7566-435a-82d1-cc1923ff24acEnglishSymplectic Elements at Oxford2006Karim, APandit, HMurray, JWandless, FThomas, NWe sought to determine whether smoking affected the outcome of reconstruction of the anterior cruciate ligament. We analysed the results of 66 smokers (group 1 with a mean follow-up of 5.67 years (1.1 to 12.7)) and 238 non-smokers (group 2 with a mean follow-up of 6.61 years (1.2 to 11.5)), who were statistically similar in age, gender, graft type, fixation and associated meniscal and chondral pathology. The assessment was performed using the International Knee Documentation Committee form and serial cruciometer readings. Poor outcomes were reported in group 1 for the mean subjective International Knee Documentation Committee score (p < 0.001), the frequency (p = 0.005) and intensity (p = 0.005) of pain, a side-to-side difference in knee laxity (p = 0.001) and the use of a four-strand hamstring graft (p = 0.015). Patients in group 1 were also less likely to return to their original level of pre-injury sport (p = 0.003) and had an overall worse final 7 International Knee Documentation Committee grade score (p = 0.007). Despite the well-known negative effects of smoking on tissue healing, the association with an inferior outcome after reconstruction of the anterior cruciate ligament has not previously been described and should be included in the pre-operative counselling of patients undergoing the procedure.
spellingShingle Karim, A
Pandit, H
Murray, J
Wandless, F
Thomas, N
Smoking and reconstruction of the anterior cruciate ligament.
title Smoking and reconstruction of the anterior cruciate ligament.
title_full Smoking and reconstruction of the anterior cruciate ligament.
title_fullStr Smoking and reconstruction of the anterior cruciate ligament.
title_full_unstemmed Smoking and reconstruction of the anterior cruciate ligament.
title_short Smoking and reconstruction of the anterior cruciate ligament.
title_sort smoking and reconstruction of the anterior cruciate ligament
work_keys_str_mv AT karima smokingandreconstructionoftheanteriorcruciateligament
AT pandith smokingandreconstructionoftheanteriorcruciateligament
AT murrayj smokingandreconstructionoftheanteriorcruciateligament
AT wandlessf smokingandreconstructionoftheanteriorcruciateligament
AT thomasn smokingandreconstructionoftheanteriorcruciateligament