The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains

The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains

The linear ubiquitin chain assembly complex (LUBAC) is the only known ubiquitin ligase for linear/Met1-linked ubiquitin chain formation. One of the LUBAC components, heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1L), was recently shown to catalyse oxyester bond formation between ubiquitin and some sub...

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Bibliographic Details
Main Authors:	Rodriguez Carvajal, A, Grishkovskaya, I, Gomez Diaz, C, Vogel, A, Sonn-Segev, A, Kushwah, MS, Schodl, K, Deszcz, L, Orban-Nemeth, Z, Sakamoto, S, Mechtler, K, Kukura, P, Clausen, T, Haselbach, D, Ikeda, F
Format:	Journal article
Language:	English
Published:	eLife Sciences Publications 2021

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