Comparison of CD22 binding to native CD45 and synthetic oligosaccharide.

Comparison of CD22 binding to native CD45 and synthetic oligosaccharide.

The B cell surface molecule CD22 is a member of the Siglec family. Siglecs possess a conserved membrane-distal immunoglobulin domain that mediates binding to sialylated glycoproteins or glycolipids. Although the structural basis of sialic acid recognition by Siglecs is quite well understood, the bin...

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Detalhes bibliográficos
Main Authors:	Bakker, T, Piperi, C, Davies, E, Merwe, P
Formato:	Journal article
Idioma:	English
Publicado em:	2002

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