High-resolution mass spectrometry of small molecules bound to membrane proteins
Small molecules are known to stabilize membrane proteins and to modulate their function and oligomeric state, but such interactions are often hard to precisely define. Here we develop and apply a high-resolution, Orbitrap mass spectrometry–based method for analyzing intact membrane protein–ligand co...
Main Authors: | Gault, J, Donlan, J, Liko, I, Hopper, J, Gupta, K, Housden, N, Struwe, W, Marty, M, Mize, T, Bechara, C, Zhu, Y, Wu, B, Kleanthous, C, Belov, M, Damoc, E, Makarov, A, Robinson, C |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2016
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