The activating NKG2D ligand MHC class I-related chain A transfers from target cells to NK cells in a manner that allows functional consequences.
Recently, it has become apparent that surface proteins commonly transfer between immune cells in contact. Inhibitory receptors and ligands exchange between cells during NK cell surveillance and we report here that NK cells also acquire activating ligands from target cells. Specifically, the stress-i...
Main Authors: | McCann, F, Eissmann, P, Onfelt, B, Leung, R, Davis, D |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2007
|
Similar Items
-
Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D.
by: Eleme, K, et al.
Published: (2004) -
Endothelial cells express NKG2D ligands and desensitize antitumor NK responses
by: Thornton W Thompson, et al.
Published: (2017-12-01) -
NKG2D+CD4+ T Cells Kill Regulatory T Cells in a NKG2D-NKG2D Ligand- Dependent Manner in Systemic Lupus Erythematosus
by: Di Yang, et al.
Published: (2017-04-01) -
Editorial: Comparative Genetics of NK Cell Receptor Families in Relation to MHC Class I Ligands and Their Function
by: Lutz Walter, et al.
Published: (2020-04-01) -
Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-rich membrane domains at the human NK cell immune synapse.
by: Endt, J, et al.
Published: (2007)