An update on indications for platelet transfusion
Platelets are very commonly prescribed blood components and in many settings their use is increasing. They may be used either prophylactically (to attempt to prevent bleeding) or therapeutically (to treat bleeding when it occurs). This review provides a summary of the major clinical settings in whic...
| Main Authors: | , , , , |
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| Format: | Journal article |
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Wiley
2016
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| _version_ | 1797056426940563456 |
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| author | Wood, E Crighton, G Estcourt, L McQuilten, Z Stanworth, S |
| author_facet | Wood, E Crighton, G Estcourt, L McQuilten, Z Stanworth, S |
| author_sort | Wood, E |
| collection | OXFORD |
| description | Platelets are very commonly prescribed blood components and in many settings their use is increasing. They may be used either prophylactically (to attempt to prevent bleeding) or therapeutically (to treat bleeding when it occurs). This review provides a summary of the major clinical settings in which platelet transfusions are currently used. Most platelet transfusions are provided prophylactically to thrombocytopenic haematology/oncology patients, although bleeding risks and rates appear to vary substantially between individual patients. Other contexts include major haemorrhage, surgery and invasive procedures, and patients in critical care and neonatal intensive care. Since platelet transfusions carry risks and costs, and evidence of benefit for platelet transfusion in many clinical settings is not yet available, additional clinical studies to establish the utility of platelet transfusions and other interventions to prevent or manage bleeding are needed. |
| first_indexed | 2024-03-06T19:22:52Z |
| format | Journal article |
| id | oxford-uuid:1ab0b378-ae3e-4c93-bb1b-250fbb0bf1dd |
| institution | University of Oxford |
| last_indexed | 2024-03-06T19:22:52Z |
| publishDate | 2016 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:1ab0b378-ae3e-4c93-bb1b-250fbb0bf1dd2022-03-26T10:56:16ZAn update on indications for platelet transfusionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1ab0b378-ae3e-4c93-bb1b-250fbb0bf1ddSymplectic Elements at OxfordWiley2016Wood, ECrighton, GEstcourt, LMcQuilten, ZStanworth, SPlatelets are very commonly prescribed blood components and in many settings their use is increasing. They may be used either prophylactically (to attempt to prevent bleeding) or therapeutically (to treat bleeding when it occurs). This review provides a summary of the major clinical settings in which platelet transfusions are currently used. Most platelet transfusions are provided prophylactically to thrombocytopenic haematology/oncology patients, although bleeding risks and rates appear to vary substantially between individual patients. Other contexts include major haemorrhage, surgery and invasive procedures, and patients in critical care and neonatal intensive care. Since platelet transfusions carry risks and costs, and evidence of benefit for platelet transfusion in many clinical settings is not yet available, additional clinical studies to establish the utility of platelet transfusions and other interventions to prevent or manage bleeding are needed. |
| spellingShingle | Wood, E Crighton, G Estcourt, L McQuilten, Z Stanworth, S An update on indications for platelet transfusion |
| title | An update on indications for platelet transfusion |
| title_full | An update on indications for platelet transfusion |
| title_fullStr | An update on indications for platelet transfusion |
| title_full_unstemmed | An update on indications for platelet transfusion |
| title_short | An update on indications for platelet transfusion |
| title_sort | update on indications for platelet transfusion |
| work_keys_str_mv | AT woode anupdateonindicationsforplatelettransfusion AT crightong anupdateonindicationsforplatelettransfusion AT estcourtl anupdateonindicationsforplatelettransfusion AT mcquiltenz anupdateonindicationsforplatelettransfusion AT stanworths anupdateonindicationsforplatelettransfusion AT woode updateonindicationsforplatelettransfusion AT crightong updateonindicationsforplatelettransfusion AT estcourtl updateonindicationsforplatelettransfusion AT mcquiltenz updateonindicationsforplatelettransfusion AT stanworths updateonindicationsforplatelettransfusion |