Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.
Many different chromosomal translocations occur in man at chromosome 11q23 in acute leukaemias. Molecular analyses revealed that the MLL gene (also called ALL-1, HRX or HTRX) is broken by the translocations, causing fusion with genes from other chromosomes. The diversity of MLL fusion partners poses...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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