Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice
Neural tube defects (NTDs), including spina bifida and anencephaly, are common birth defects whose complex multigenic causation has hampered efforts to delineate their molecular basis. The effect of putative modifier genes in determining NTD susceptibility may be investigated in mouse models, partic...
Main Authors: | De Castro, S, Malhas, A, Leung, K, Gustavsson, P, Vaux, D, Copp, A, Greene, N |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2012
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