Promoter proximal splice sites enhance transcription.
Reconstruction of a gene with its introns removed results in reduced levels of cytoplasmic mRNA. This is partly explained by introns promoting the export of mRNA through coupling splicing to nuclear export processes. However, we show here that splicing signals can have a direct role in enhancing gen...
Main Authors: | Furger, A, O'Sullivan, J, Binnie, A, Lee, B, Proudfoot, N |
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Format: | Journal article |
Language: | English |
Published: |
2002
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