A ryanodine receptor-like molecule expressed in the osteoclast plasma membrane functions in extracellular Ca2+ sensing.

A ryanodine receptor-like molecule expressed in the osteoclast plasma membrane functions in extracellular Ca2+ sensing.

Ryanodine receptors (RyRs) reside in microsomal membranes where they gate Ca2+ release in response to changes in the cytosolic Ca2+ concentration. In the osteoclast, a divalent cation sensor, the Ca2+ receptor (CaR), located within the cell's plasma membrane, monitors changes in the extracellul...

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Detalles Bibliográficos
Autores principales: Zaidi, M, Shankar, V, Tunwell, R, Adebanjo, O, Mackrill, J, Pazianas, M, O'Connell, D, Simon, B, Rifkin, B, Venkitaraman, A
Formato: Journal article
Lenguaje:English
Publicado: 1995

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