Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex.

Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex.

The 22 members of the fibroblast growth factor (FGF) family have been implicated in cell proliferation, differentiation, survival, and migration. They are required for both development and maintenance of vertebrates, demonstrating an exquisite pattern of affinities for both protein and proteoglycan...

Full description

Bibliographic Details
Main Authors:	Harmer, N, Ilag, L, Mulloy, B, Pellegrini, L, Robinson, C, Blundell, T
Format:	Journal article
Language:	English
Published:	2004

Similar Items

Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.
by: Harmer, N, et al.
Published: (2006)

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin.
by: Pellegrini, L, et al.
Published: (2000)

Myocardial protection by heparin-based coacervate of FGF10
by: Zhouguang Wang, et al.
Published: (2021-07-01)

Variation in the fibroblast growth factor 23 (FGF23) gene associates with serum FGF23 and bone strength in infants
by: Maria Enlund-Cerullo, et al.
Published: (2023-05-01)

Computer-assisted stabilization of fibroblast growth factor FGF-18
by: Jan Vilim, et al.
Published: (2023-01-01)

Disruption of FGF2-Heparin-FGFR1 Complex Formation by Antiangiogenic Small Molecule Found In Silico
by: Mahdiyeh Sadat Mahdavi, et al.
Published: (2017-06-01)

Complexation of CXCL12, FGF-2 and VEGF with Heparin Modulates the Protein Release from Alginate Microbeads
by: Edyta Adrian, et al.
Published: (2021-10-01)

Fibroblast Growth Factor (FGF) Receptor Mutations: A Pathway to Understanding Multigenic Risk in Disease?
by: Stuart J. Mires
Published: (2013-12-01)

Fibroblast Growth Factor (FGF) Receptor Mutations: A Pathway to Understanding Multigenic Risk in Disease?
by: Stuart J. Mires
Published: (2013-12-01)

Hair Growth Regulation by Fibroblast Growth Factor 12 (FGF12)
by: Jiwon Woo, et al.
Published: (2022-08-01)

Constitutive and Regulated Shedding of Soluble FGF Receptors Releases Biologically Active Inhibitors of FGF-2
by: Anne Hanneken, et al.
Published: (2021-03-01)

Fibroblast Growth Factor 2 (FGF2) in cartilage injury and repair
by: Khan, S
Published: (2018)

The Role of Fibroblast Growth Factor (FGF) Signaling in Tissue Repair and Regeneration
by: Mariya Farooq, et al.
Published: (2021-11-01)

Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors
by: Zuyao Chen, et al.
Published: (2023-05-01)

The Effects of Fibroblast Growth Factor-2 (FGF-2) on Achilles Tendon Injury
by: Yuki Fujikawa D(Orth), et al.
Published: (2023-12-01)

Expression of FGF8, FGF18, and FGFR4 in Gastroesophageal Adenocarcinomas
by: Gerd Jomrich, et al.
Published: (2019-09-01)

Shedding Light on the Complex Regulation of FGF23
by: Marc G. Vervloet
Published: (2022-04-01)

New Aspects of the Kidney in the Regulation of Fibroblast Growth Factor 23 (FGF23) and Mineral Homeostasis
by: Maria L. Mace, et al.
Published: (2020-11-01)

Dissecting the Interaction of FGF8 with Receptor FGFRL1
by: Lei Zhuang, et al.
Published: (2020-10-01)

The Suitability of FGF21 and FGF23 as New Biomarkers in Endometrial Cancer Patients
by: Aneta Cymbaluk-Płoska, et al.
Published: (2020-06-01)

Biological and pharmacological functions of the FGF19- and FGF21-coreceptor beta klotho
by: Alexandra S. Aaldijk, et al.
Published: (2023-05-01)

<it>VEGF</it>, <it>FGF1</it>, <it>FGF2 </it>and <it>EGF </it>gene polymorphisms and psoriatic arthritis
by: Rahman Proton, et al.
Published: (2007-01-01)

Basic fibroblast growth factor (FGF) mediator of the immediate injury response in articular cartilage
by: Vincent, T, et al.
Published: (2001)

Effect of Fibroblast Growth Factor (FGF) on Some Serum Oxidative Parameters in Hyperglycemic Rats
by: Şule Coşkun Cevher, et al.
Published: (2021-12-01)

Liver-brain axis with alcohol: Role of fibroblast growth factor 21 (FGF21)
by: Ke Zhang, et al.
Published: (2024-03-01)

Targeting fibroblast growth factor (FGF)-inducible 14 (Fn14) for tumor therapy
by: Olena Zaitseva, et al.
Published: (2022-10-01)

Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1).
by: Torunn Sletten, et al.
Published: (2014-01-01)

Effects of TGFbeta and bFGF on the differentiation of human bone marrow stromal fibroblasts.
by: Locklin, R, et al.
Published: (1999)

Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter
by: Songwei Feng, et al.
Published: (2024-03-01)

Fibroblast growth factor receptor 4 (FGF4) and fibroblast growth factor 19 (FGFR19) autocrine enhance brest cancer cells survival
by: Tiong, Kai Hung, et al.
Published: (2016)

FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development
by: Long Jason E, et al.
Published: (2008-07-01)

Characterization of the biological properties of FGF-9
by: Seet, L, et al.
Published: (1996)

Fibroblast Growth Factor 11 (FGF11) Promotes Progression and Cisplatin Resistance Through the HIF-1α/FGF11 Signaling Axis in Ovarian Clear Cell Carcinoma
by: Yin M, et al.
Published: (2023-07-01)

BASIC FIBROBLAST GROWTH FACTOR (bFGF) MEDIATES THE IMMEDIATE INJURY RESPONSE IN ARTICULAR CARTILAGE
by: Vincent, T, et al.
Published: (2002)

Fibroblast Growth Factor-2 (FGF-2) Expression in Pterygia Using Cell Spot Arrays
by: Stylianos Mastronikolis, et al.
Published: (2022-09-01)

FGF23, Biomarker or Target?
by: Cristian Rodelo-Haad, et al.
Published: (2019-03-01)

FGF21 and cardiac physiopathology
by: Anna ePlanavila, et al.
Published: (2015-08-01)

Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish.
by: Matthew N McCarroll, et al.
Published: (2013-01-01)

Fibroblast growth factor-21 (FGF21) analogs as possible treatment options for diabetes mellitus in veterinary patients
by: Ronald J. Corbee, et al.
Published: (2023-01-01)

Infigratinib Reduces Fibroblast Growth Factor 23 (FGF23) and Increases Blood Phosphate in Tumor‐Induced Osteomalacia
by: Iris R. Hartley, et al.
Published: (2022-08-01)