Drosophila Spd-2 recruits PCM to the sperm centriole, but is dispensable for centriole duplication.
In C. elegans, genome-wide screens have identified just five essential centriole-duplication factors: SPD-2, ZYG-1, SAS-5, SAS-6, and SAS-4 [1-8]. These proteins are widely believed to comprise a conserved core duplication module [3, 9-14]. In worm embryos, SPD-2 is the most upstream component of th...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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