Adjunctive dexamethasone in HIV-associated cryptococcal meningitis

Adjunctive dexamethasone in HIV-associated cryptococcal meningitis

Cryptococcal meningitis associated with human immunodeficiency virus (HIV) infection causes more than 600,000 deaths each year worldwide. Treatment has changed little in 20 years, and there are no imminent new anticryptococcal agents. The use of adjuvant glucocorticoids reduces mortality among patie...

Full description

Bibliographic Details
Main Authors:	Beardsley, J, Wolbers, M, Kibengo, F, Ggayi, A, Kamali, A, Cuc, N, Binh, T, Chau, N, Farrar, J, Merson, L, Phuong, L, Thwaites, G, Van Kinh, N, Thuy, P, Chierakul, W, Siriboon, S, Thiansukhon, E, Onsanit, S, Supphamongkholchaikul, W, Chan, A, Heyderman, R, Mwinjiwa, E, van Oosterhout, J, Imran, D, Basri, H, Mayxay, M, Dance, D, Phimmasone, P, Rattanavong, S, Lalloo, D, Day, J
Format:	Journal article
Language:	English
Published:	Massachusetts Medical Society 2016

Similar Items

Do intracerebral cytokine responses explain the harmful effects of dexamethasone in HIV-associated cryptococcal meningitis?
by: Beardsley, J, et al.
Published: (2018)

CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial.
by: Day, N, et al.
Published: (2014)

The authors reply: Dexamethasone in Cryptococcal Meningitis
by: Beardsley, J, et al.
Published: (2016)

Combination antifungal therapy for cryptococcal meningitis.
by: Day, J, et al.
Published: (2013)

Population pharmacokinetics and cerebrospinal fluid penetration of fluconazole in adults with cryptococcal meningitis
by: Stott, K, et al.
Published: (2018)

Determinants of two-year mortality among HIV positive patients with Cryptococcal meningitis initiating standard antifungal treatment with or without adjunctive dexamethasone in Uganda
by: Kitonsa, J, et al.
Published: (2020)

Population pharmacokinetic model and meta-analysis of outcomes of amphotericin B deoxycholate use in adults with cryptococcal meningitis
by: Stott, K, et al.
Published: (2018)

A model CNS fungal infection: cryptococcal meningitis
by: Beardsley, J, et al.
Published: (2015)

A randomized open label trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis
by: Ngan, N, et al.
Published: (2019)

Quality of life and associated factors among HIV positive patients after completion of treatment for Cryptococcal meningitis
by: Kitonsa, J, et al.
Published: (2021)

Combination antifungal therapy for cryptococcal meningitis.
by: Day, J, et al.
Published: (2013)

Cryptococcal meningitis
by: Day, J
Published: (2004)

Cryptococcal choroidoretinitis and immunodeficiency.
by: Church, W, et al.
Published: (1987)

An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis
by: Ngan, NTT, et al.
Published: (2021)

Sertraline for HIV-associated cryptococcal meningitis.
by: Veringa, A, et al.
Published: (2016)

Cryptococcal meningitis: a neglected NTD?
by: Molloy, S, et al.
Published: (2017)

IFN-gamma at the site of infection determines rate of clearance of infection in cryptococcal meningitis.
by: Siddiqui, A, et al.
Published: (2005)

A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis.
by: Newton, P, et al.
Published: (2002)

A CASE OF SARCOIDOSIS WITH CRYPTOCOCCAL MENINGITIS
by: Scadding, J, et al.
Published: (1969)

Oral versus intravenous flucytosine in patients with human immunodeficiency virus-associated cryptococcal meningitis.
by: Brouwer, A, et al.
Published: (2007)

Combination antifungal therapies for HIV-associated cryptococcal meningitis: a randomised trial.
by: Brouwer, A, et al.
Published: (2004)

Cerebrospinal fluid HIV-1 viral load during treatment of cryptococcal Meningitis.
by: Brouwer, A, et al.
Published: (2010)

In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.
by: Larsen, R, et al.
Published: (2007)

Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries
by: Loyse, A, et al.
Published: (2018)

Open access clinical trials in cryptococcal meningitis
by: Day, J
Published: (2014)

Baseline correlation and comparative kinetics of cerebrospinal fluid colony-forming unit counts and antigen titers in cryptococcal meningitis.
by: Brouwer, A, et al.
Published: (2005)

A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease
by: Chau, T, et al.
Published: (2010)

Benefits of enhanced infection prophylaxis at antiretroviral therapy initiation by cryptococcal antigen status
by: Pett, SL, et al.
Published: (2020)

Antifungal susceptibility does not correlate with fungal clearance or survival in AIDS associated cryptococcal meningitis
by: O'Connor, L, et al.
Published: (2020)

MRI and CT findings of cryptococcal vaginitis
by: Ranganathan, S., et al.
Published: (2005)

Massive pleural effusions in cryptococcal meningitis.
by: Wong, C.M., et al.
Published: (1999)

Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures.
by: Bicanic, T, et al.
Published: (2009)

Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes.
by: Jarvis, J, et al.
Published: (2014)

Bilateral optic neuropathy in acute cryptococcal meningitis
by: Qi, Zhe Ngoo, et al.
Published: (2016)

Independent association between rate of clearance of infection and clinical outcome of HIV-associated cryptococcal meningitis: analysis of a combined cohort of 262 patients.
by: Bicanic, T, et al.
Published: (2009)

Statistical Analysis Code: AN OPEN LABEL RANDOMIZED CONTROLLED TRIAL OF TAMOXIFEN COMBINED WITH AMPHOTERICIN B AND FLUCONAZOLE FOR CRYPTOCOCCAL MENINGITIS
by: Ngan, N, et al.
Published: (2021)

Extended data - Appendices - A randomised controlled trial of tamoxifen for cryptococcal meningitis
by: Day, J
Published: (2019)

Most cases of cryptococcal meningitis in HIV-uninfected patients in Vietnam are due to a distinct amplified fragment length polymorphism-defined cluster of Cryptococcus neoformans var. grubii VN1.
by: Day, J, et al.
Published: (2011)

Cryptococcal meningitis disguised as a stroke: a case report
by: Muhamad Damanhuri, Fatimahtuz Zahrah, et al.
Published: (2022)

Cryptococcal meningitis in an immunocompetent swiftlet rancher – first reported case
by: Tan, Sin Nee, et al.
Published: (2019)