Serial analysis of gene expression provides new insights into regulatory T cells.
It is now possible to induce donor-specific transplantation tolerance in adult rodents using a number of therapeutic strategies. Such peripheral tolerance is maintained by regulatory CD4+ T cells, not only in transplantation models, but also in autoimmunity. Differential gene expression analyses hav...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2003
|
| _version_ | 1797056521143582720 |
|---|---|
| author | Cobbold, S Adams, E Graca, L Waldmann, H |
| author_facet | Cobbold, S Adams, E Graca, L Waldmann, H |
| author_sort | Cobbold, S |
| collection | OXFORD |
| description | It is now possible to induce donor-specific transplantation tolerance in adult rodents using a number of therapeutic strategies. Such peripheral tolerance is maintained by regulatory CD4+ T cells, not only in transplantation models, but also in autoimmunity. Differential gene expression analyses have been used to identify potential new markers for regulatory T cells, aiming to reveal new insights into their mechanisms of action, and to find novel targets for therapeutic manipulation of the immune system. |
| first_indexed | 2024-03-06T19:23:51Z |
| format | Journal article |
| id | oxford-uuid:1b0b5a86-e467-40fa-baee-d3706aae26d1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:23:51Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:1b0b5a86-e467-40fa-baee-d3706aae26d12022-03-26T10:58:05ZSerial analysis of gene expression provides new insights into regulatory T cells.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1b0b5a86-e467-40fa-baee-d3706aae26d1EnglishSymplectic Elements at Oxford2003Cobbold, SAdams, EGraca, LWaldmann, HIt is now possible to induce donor-specific transplantation tolerance in adult rodents using a number of therapeutic strategies. Such peripheral tolerance is maintained by regulatory CD4+ T cells, not only in transplantation models, but also in autoimmunity. Differential gene expression analyses have been used to identify potential new markers for regulatory T cells, aiming to reveal new insights into their mechanisms of action, and to find novel targets for therapeutic manipulation of the immune system. |
| spellingShingle | Cobbold, S Adams, E Graca, L Waldmann, H Serial analysis of gene expression provides new insights into regulatory T cells. |
| title | Serial analysis of gene expression provides new insights into regulatory T cells. |
| title_full | Serial analysis of gene expression provides new insights into regulatory T cells. |
| title_fullStr | Serial analysis of gene expression provides new insights into regulatory T cells. |
| title_full_unstemmed | Serial analysis of gene expression provides new insights into regulatory T cells. |
| title_short | Serial analysis of gene expression provides new insights into regulatory T cells. |
| title_sort | serial analysis of gene expression provides new insights into regulatory t cells |
| work_keys_str_mv | AT cobbolds serialanalysisofgeneexpressionprovidesnewinsightsintoregulatorytcells AT adamse serialanalysisofgeneexpressionprovidesnewinsightsintoregulatorytcells AT gracal serialanalysisofgeneexpressionprovidesnewinsightsintoregulatorytcells AT waldmannh serialanalysisofgeneexpressionprovidesnewinsightsintoregulatorytcells |