Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15.
Two types of exogenous K channel were identified in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting cell line HIT T15. One of these was the ATP-regulated K channel (G channel) as evidenced by its conductance and inhibition by tolbutamide. The other resembled the Ca-acti...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1988
|
| _version_ | 1797056541425139712 |
|---|---|
| author | Ashcroft, F Ashcroft, S Berggren, P Betzholz, C Rorsman, P Trube, G Welsh, M |
| author_facet | Ashcroft, F Ashcroft, S Berggren, P Betzholz, C Rorsman, P Trube, G Welsh, M |
| author_sort | Ashcroft, F |
| collection | OXFORD |
| description | Two types of exogenous K channel were identified in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting cell line HIT T15. One of these was the ATP-regulated K channel (G channel) as evidenced by its conductance and inhibition by tolbutamide. The other resembled the Ca-activated K channel from beta-cells. |
| first_indexed | 2024-03-06T19:24:06Z |
| format | Journal article |
| id | oxford-uuid:1b220682-606d-4080-9b1f-f4b8c1c2fb7e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:24:06Z |
| publishDate | 1988 |
| record_format | dspace |
| spelling | oxford-uuid:1b220682-606d-4080-9b1f-f4b8c1c2fb7e2022-03-26T10:58:34ZExpression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1b220682-606d-4080-9b1f-f4b8c1c2fb7eEnglishSymplectic Elements at Oxford1988Ashcroft, FAshcroft, SBerggren, PBetzholz, CRorsman, PTrube, GWelsh, MTwo types of exogenous K channel were identified in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting cell line HIT T15. One of these was the ATP-regulated K channel (G channel) as evidenced by its conductance and inhibition by tolbutamide. The other resembled the Ca-activated K channel from beta-cells. |
| spellingShingle | Ashcroft, F Ashcroft, S Berggren, P Betzholz, C Rorsman, P Trube, G Welsh, M Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15. |
| title | Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15. |
| title_full | Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15. |
| title_fullStr | Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15. |
| title_full_unstemmed | Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15. |
| title_short | Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15. |
| title_sort | expression of k channels in xenopus laevis oocytes injected with poly a mrna from the insulin secreting beta cell line hit t15 |
| work_keys_str_mv | AT ashcroftf expressionofkchannelsinxenopuslaevisoocytesinjectedwithpolyamrnafromtheinsulinsecretingbetacelllinehitt15 AT ashcrofts expressionofkchannelsinxenopuslaevisoocytesinjectedwithpolyamrnafromtheinsulinsecretingbetacelllinehitt15 AT berggrenp expressionofkchannelsinxenopuslaevisoocytesinjectedwithpolyamrnafromtheinsulinsecretingbetacelllinehitt15 AT betzholzc expressionofkchannelsinxenopuslaevisoocytesinjectedwithpolyamrnafromtheinsulinsecretingbetacelllinehitt15 AT rorsmanp expressionofkchannelsinxenopuslaevisoocytesinjectedwithpolyamrnafromtheinsulinsecretingbetacelllinehitt15 AT trubeg expressionofkchannelsinxenopuslaevisoocytesinjectedwithpolyamrnafromtheinsulinsecretingbetacelllinehitt15 AT welshm expressionofkchannelsinxenopuslaevisoocytesinjectedwithpolyamrnafromtheinsulinsecretingbetacelllinehitt15 |