Next-generation sequencing identifies germline MRE11A variants as markers of radiotherapy outcomes in muscle-invasive bladder cancer

Next-generation sequencing identifies germline MRE11A variants as markers of radiotherapy outcomes in muscle-invasive bladder cancer

Background Muscle-invasive bladder cancer (MIBC) can be cured by radical radiotherapy (RT). We previously found tumour MRE11 expression to be predictive of survival following RT in MIBC, and this was independently validated in a separate institute. Here, we investigated germline MRE11A variants as p...

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Bibliographic Details
Main Authors: Teo, M, Dyrskjøt, L, Nsengimana, J, Buchwald, C, Snowden, H, Morgan, J, Jensen, J, Knowles, M, Taylor, G, Barrett, J, Borre, M, Orntoft, T, Bishop, D, Kiltie, A
Format: Journal article
Language:English
Published: Oxford University Press 2014

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