A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy is a conserved constitutive cellular process, responsible for the degradation of dysfunctional proteins and organelles. Autophagy plays a role in many diseases such as neurodegeneration and cancer; however, to date, conventional autophagy detection techniques are not suitable for clinical...
Main Authors: | Phadwal, K, Alegre-Abarrategui, J, Watson, A, Pike, L, Anbalagan, S, Hammond, E, Wade-Martins, R, McMichael, A, Klenerman, P, Simon, A |
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Format: | Journal article |
Language: | English |
Published: |
2012
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