Protocol for a double-blind placebo-controlled randomised controlled trial assessing the impact of oral semaglutide in amyloid positivity (ISAP) in community dwelling UK adults
Introduction: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), currently marketed for type 2 diabetes and obesity, may offer novel mechanisms to delay or prevent neurotoxicity associated with Alzheimer’s disease (AD). The impact of semaglutide in amyloid positivity (ISAP) trial is investigatin...
Main Authors: | Koychev, I, Adler, AI, Edison, P, Tom, B, Milton, JE, Butchart, J, Hampshire, A, Marshall, C, Coulthard, E, Zetterberg, H, Hellyer, P, Cormack, F, Underwood, BR, Mummery, CJ, Holman, RR |
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Format: | Journal article |
Language: | English |
Published: |
BMJ Publishing Group
2024
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