The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease.

Alpha-Synuclein is thought to play an important role in the pathology of Parkinson's disease (PD). Truncated forms of this protein can be found in PD brain extracts, and these species aggregate faster and are more susceptible to oxidative stress than the full-length protein. We investigated the...

Full description

Bibliographic Details
Main Authors: Michell, A, Tofaris, G, Gossage, H, Tyers, P, Spillantini, MG, Barker, R
Format: Journal article
Language:English
Published: 2007

Similar Items