Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells
The formation of the immunological synapse between a T cell and the antigen-presenting cell (APC) is critically dependent on actin dynamics, downstream of T cell receptor (TCR) and integrin (LFA-1) signalling. There is also accumulating evidence that mechanical forces, generated by actin polymerizat...
Hlavní autoři: | Tabdanov, E, Gondarenko, S, Kumari, S, Liapis, A, Dustin, M, Sheetz, M, Kam, L, Iskratsch, T |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Royal Society of Chemistry
2015
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