Wnt2 is a direct downstream target of GATA6 during early cardiogenesis.
The GATA4, 5 and 6 subfamily of transcription factors are potent transactivators of transcription expressed within the precardiac mesoderm. However, little is known of the immediate downstream targets of GATA-factor regulation during the earliest stages of cardiogenesis. Using the P19-CL6 embryonal...
Váldodahkkit: | Alexandrovich, A, Arno, M, Patient, R, Shah, A, Pizzey, J, Brewer, A |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2006
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Geahča maid
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GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis.
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Widespread expression of an extended peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of RNA and protein expression domains.
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