Racemisation and rearrangement of 1,2-dihydro-1,3,5-triazines: a novel reversible thermal electrocyclic reaction
Chiral 1,2-diaryl-1,2-dihydro-4,6-diamino-1,3,5-triazines undergo facile racemisation by a reversible thermal electrocyclic reaction mechanism; the transient intermediate can lead, after tautomerisation, to rearranged racemic 2-aryl-1,2-dihydro-4-amino-6-anilino-1,3,5-triazines.
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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| Summary: | Chiral 1,2-diaryl-1,2-dihydro-4,6-diamino-1,3,5-triazines undergo facile racemisation by a reversible thermal electrocyclic reaction mechanism; the transient intermediate can lead, after tautomerisation, to rearranged racemic 2-aryl-1,2-dihydro-4-amino-6-anilino-1,3,5-triazines. |
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