Integrating ion mobility mass spectrometry with molecular modelling to determine the architecture of multiprotein complexes.
Current challenges in the field of structural genomics point to the need for new tools and technologies for obtaining structures of macromolecular protein complexes. Here, we present an integrative computational method that uses molecular modelling, ion mobility-mass spectrometry (IM-MS) and incompl...
Glavni autori: | Politis, A, Park, A, Hyung, S, Barsky, D, Ruotolo, B, Robinson, C |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
2010
|
Slični predmeti
-
Ion mobility-mass spectrometry reveals the influence of subunit packing and charge on the dissociation of multiprotein complexes.
od: Boeri Erba, E, i dr.
Izdano: (2010) -
Mass spectrometry characterization of multiprotein complexes.
od: Robinson, C
Izdano: (2009) -
Ion mobility-mass spectrometry analysis of large protein complexes.
od: Ruotolo, B, i dr.
Izdano: (2008) -
Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements.
od: Pukala, T, i dr.
Izdano: (2009) -
Gas-phase unfolding and disassembly reveals stability differences in ligand-bound multiprotein complexes.
od: Hyung, S, i dr.
Izdano: (2009)