Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension

Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension

Detalles Bibliográficos
Main Authors:	Chen, A, Du, Y, Galligan, J, Fink, G, Alp, N, Channon, K
Formato:	Conference item
Publicado:	2005

Títulos similares

Endothelial-specific GTP cyclohydrolase overexpression reduces blood pressure in salt-sensitive hypertension
por: Chen, A, et al.
Publicado: (2006)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
por: Du, Y, et al.
Publicado: (2005)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
por: Du, Y, et al.
Publicado: (2005)

Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
por: Du, Y, et al.
Publicado: (2008)

Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
por: Chen, A, et al.
Publicado: (2005)

Endothelial-targeted GTP cyclohydrolase I overexpression increases endothelial tetrahydrobiopterin levels and preserves eNOS coupling in eNOS overexpressing mice
por: Bendall, J, et al.
Publicado: (2004)

Endotoxemia-related acute kidney injury in transgenic mice with endothelial overexpression of GTP cyclohydrolase-1.
por: Wang, W, et al.
Publicado: (2008)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
por: Chuaiphichai, S, et al.
Publicado: (2014)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
por: Chuaiphichai, S, et al.
Publicado: (2014)

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
por: Alp, N, et al.
Publicado: (2004)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
por: Alp, N, et al.
Publicado: (2003)

GTP cyclohydrolase I deficiency results in oxidative stress and pulmonary hypertension
por: Khoo, J, et al.
Publicado: (2004)

303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
por: Chuaiphichai, S, et al.
Publicado: (2014)

Cardiomyocyte-Targeted Overexpression of GTP Cyclohydrolase-1 Increases Myocyte Lusitropy and Reduces Superoxide Production
por: Carnicer, R, et al.
Publicado: (2010)

Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
por: Chuaiphichai, S, et al.
Publicado: (2021)

GTP Cyclohydrolase/BH4 Pathway Protects EPC Function via Suppressing Oxidative Stress and Thrombospondin-1 in Salt-Sensitive Hypertension
por: Xie, H, et al.
Publicado: (2009)

Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
por: Carnicer, R, et al.
Publicado: (2011)

GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension
por: Xie, H, et al.
Publicado: (2010)

GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension.
por: Xie, H, et al.
Publicado: (2010)

GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
por: Tatham, A, et al.
Publicado: (2009)

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
por: Bendall, J, et al.
Publicado: (2005)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
por: Alp, N, et al.
Publicado: (2003)

Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection.
por: Ionova, I, et al.
Publicado: (2010)

Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.
por: Liao, S, et al.
Publicado: (2007)

Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.
por: Starr, A, et al.
Publicado: (2014)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
por: Alp, N, et al.
Publicado: (2003)

Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes.
por: Tie, L, et al.
Publicado: (2009)

BH4 preserves endothelial progenitor cells via enhancing SDF-1 alpha and suppressing TSP-1 expression in salt-sensitive hypertension
por: Xie, H, et al.
Publicado: (2007)

PRESERVATION OF ENDOTHELIAL GTP CYCLOHYDROLASE I ACTIVITY AND IMPROVEMENT OF RENAL NITRIC OXIDE AVAILABILITY PREVENT THE DEVELOPMENT OF DIABETIC NEPHROPATHY
por: Satoh, M, et al.
Publicado: (2012)

GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1.
por: Tie, L, et al.
Publicado: (2014)

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
por: Ryan, B, et al.
Publicado: (2014)

GTP cyclohydrolase II structure and mechanism.
por: Ren, J, et al.
Publicado: (2005)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
por: Alp, N, et al.
Publicado: (2003)

Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.
por: Adlam, D, et al.
Publicado: (2007)

Increased GTP-cyclohydrolase I expression but not vitamin C treatment restored accelerated atherosclerotic lesion formation in apolipoprotein E-deficient mice overexpressing endothelial nitric oxide synthase
por: Takaya, T, et al.
Publicado: (2004)

Decreased Cardiac Allograft Rejection in Mice Over-Expressing Human GTP Cyclohydrolase I.
por: Irina, I, et al.
Publicado: (2009)

Genetic variation in GCH1, encoding GTP-cyclohydrolase 1, regulates biopterin levels and endothelial function in atherosclerosis
por: Van, A, et al.
Publicado: (2008)

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
por: Cai, S, et al.
Publicado: (2002)

Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
por: Alp, N, et al.
Publicado: (2002)

GTP cyclohydrolase as a novel mechanism for tumour growth
por: Chen, L, et al.
Publicado: (2015)