KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.

KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.

Renewed global efforts toward malaria eradication have highlighted the need for novel antimalarial agents with activity against multiple stages of the parasite life cycle. We have previously reported the discovery of a novel class of antimalarial compounds in the imidazolopiperazine series that have...

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Bibliographic Details
Main Authors: Kuhen, K, Chatterjee, A, Rottmann, M, Gagaring, K, Borboa, R, Buenviaje, J, Chen, Z, Francek, C, Wu, T, Nagle, A, Barnes, S, Plouffe, D, Lee, M, Fidock, D, Graumans, W, van de Vegte-Bolmer, M, van Gemert, G, Wirjanata, G, Sebayang, B, Marfurt, J, Russell, B, Suwanarusk, R, Price, R, Nosten, F, Tungtaeng, A, Gettayacamin, M, Sattabongkot, J, Taylor, J, Walker, J, Tully, D, Patra, K, Flannery, E, Vinetz, J, Renia, L, Sauerwein, R, Winzeler, E, Glynne, R, Diagana, T
Format: Journal article
Language:English
Published: American Society for Microbiology 2014

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