Immunobiology of solid organ transplantation.
The field of organ transplantation is entering a very exciting phase in which tolerance induction may become a therapeutic possibility. The induction of tolerance would allow patients to enjoy the benefits of their transplanted organ without risking the mortality and morbidity associated with long-t...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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| _version_ | 1797056747079204864 |
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| author | Turvey, SE Wood, K |
| author_facet | Turvey, SE Wood, K |
| author_sort | Turvey, SE |
| collection | OXFORD |
| description | The field of organ transplantation is entering a very exciting phase in which tolerance induction may become a therapeutic possibility. The induction of tolerance would allow patients to enjoy the benefits of their transplanted organ without risking the mortality and morbidity associated with long-term pharmacological immunosuppression. In this review, we explore the immunobiology of solid organ transplantation, discussing the immunological mechanisms responsible for allograft rejection, and outlining the rational behind a range of successful experimental tolerance induction strategies. |
| first_indexed | 2024-03-06T19:26:58Z |
| format | Journal article |
| id | oxford-uuid:1c194980-5715-4443-9fc8-2febcaea69dc |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:26:58Z |
| publishDate | 1999 |
| record_format | dspace |
| spelling | oxford-uuid:1c194980-5715-4443-9fc8-2febcaea69dc2022-03-26T11:03:51ZImmunobiology of solid organ transplantation.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1c194980-5715-4443-9fc8-2febcaea69dcEnglishSymplectic Elements at Oxford1999Turvey, SEWood, KThe field of organ transplantation is entering a very exciting phase in which tolerance induction may become a therapeutic possibility. The induction of tolerance would allow patients to enjoy the benefits of their transplanted organ without risking the mortality and morbidity associated with long-term pharmacological immunosuppression. In this review, we explore the immunobiology of solid organ transplantation, discussing the immunological mechanisms responsible for allograft rejection, and outlining the rational behind a range of successful experimental tolerance induction strategies. |
| spellingShingle | Turvey, SE Wood, K Immunobiology of solid organ transplantation. |
| title | Immunobiology of solid organ transplantation. |
| title_full | Immunobiology of solid organ transplantation. |
| title_fullStr | Immunobiology of solid organ transplantation. |
| title_full_unstemmed | Immunobiology of solid organ transplantation. |
| title_short | Immunobiology of solid organ transplantation. |
| title_sort | immunobiology of solid organ transplantation |
| work_keys_str_mv | AT turveyse immunobiologyofsolidorgantransplantation AT woodk immunobiologyofsolidorgantransplantation |