T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal.
Vesicular stomatitis virus (VSV) induces a T helper cell-independent IgM antibody response, whereas the IgG response is strictly T helper cell dependent. Since VSV induces B cells in complete absence of T helper cells, the question arises as to whether this induction occurs in the absence of a secon...
Main Authors: | Fehr, T, Bachmann, M, Bluethmann, H, Kikutani, H, Hengartner, H, Zinkernagel, R |
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Format: | Journal article |
Language: | English |
Published: |
1996
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