Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic consequences independent of overall adiposity. WHR is heritable, but few genetic variants influencing this trait have been identified. We conducted a meta-analysis of 32 genome-wide association studies for WHR a...
Autori principali: | Heid, I, Jackson, A, Randall, J, Winkler, T, Qi, L, Steinthorsdottir, V, Thorleifsson, G, Zillikens, M, Speliotes, E, Mägi, R, Workalemahu, T, White, C, Bouatia-Naji, N, Harris, T, Berndt, S, Ingelsson, E, Willer, C, Weedon, M, Luan, J, Vedantam, S, Esko, T, Kilpeläinen, T, Kutalik, Z, Li, S, Monda, K |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2010
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