Low-dose nitric oxide as targeted anti-biofilm adjunctive therapy to treat chronic Pseudomonas aeruginosa infection in cystic fibrosis

Low-dose nitric oxide as targeted anti-biofilm adjunctive therapy to treat chronic Pseudomonas aeruginosa infection in cystic fibrosis

Despite aggressive antibiotic therapy, bronchopulmonary colonization by Pseudomonas aeruginosa causes persistent morbidity and mortality in cystic fibrosis (CF). Chronic P. aeruginosa infection in the CF lung is associated with structured, antibiotic-tolerant bacterial aggregates known as biofilms....

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Prif Awduron: Howlin, RP, Cathie, K, Hall-Stoodley, L, Cornelius, V, Duignan, C, Allan, RN, Fernandez, BO, Barraud, N, Bruce, KD, Jefferies, J, Kelso, M, Kjelleberg, S, Rice, SA, Rogers, GB, Pink, S, Smith, C, Sukhtankar, PS, Salib, R, Legg, J, Carroll, M, Daniels, T, Feelisch, M, Stoodley, P, Clarke, SC, Connett, G, Faust, SN, Webb, JS
Fformat: Journal article
Cyhoeddwyd: Elsevier 2017

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